avalon organics vitamin c lip balm review ErikaJjang — Healthy Options: & Alba Botanica Made with vegan Avalon Organics Moisturising Lip Balm

10.1016/s0031-9422(97)00984-9 Phytochemistry 109 HofbauerS.HagmllerA.SchaffnerI.MlynekG.KrutzlerM.StadlmayrG.et al (2015)

KPV: modulation of inflammatory pathways (inhibition of NF-B)

sometimes used for chronic pain, migraine prevention Nortriptyline (Pamelor) Moderate weight gain, less than amitriptyline Still has metabolic risks Clinical use: Sometimes used for depression when SSRIs fail, neuropathic pain Imipramine (Tofranil) Moderate weight gain Associated with metabolic syndrome in longitudinal studies Clinical use: Occasionally for treatment-resistant depression, bedwetting in children Doxepin (Sinequan) Significant weight gain Very sedating Clinical use: Sometimes used for insomnia at very low doses (Silenor) Clomipramine (Anafranil) Moderate to significant weight gain Clinical use: OCD (FDA-approved), sometimes treatment-resistant depression Overall TCA assessment: TCAs as a class carry the highest metabolic risk

See the related Commentary at The role of 15 lipoxygenase 1 in asthma comes into focus.

Inconsistences in pharmacological effects of plant-based formulations The description in the literature of different therapeutic outcomes using similar plant-derived formulations occurs with some frequency

The potential risks and benefits must be carefully weighed