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Recently, the dipeptide l-alanylglutamine was suggested to inhibit signalling proteins that trigger protein degradation following an acute bout of resistance exercise [145]

Pt-iNOS@ZIF was found to greatly reduce oxidative stress-induced damage, inhibit cell apoptosis, and reduce the expression of proinflammatory cytokines, leading to effective protection of liver IRI by eliminating ROS with generated O 2 , which further promoted the production of NO via the catalysis of iNOS

doi: 10.1515/folmed-2017-0068 24 WuJFengZChenLLiYBianHGengJet al

Similarly, khayandirobilide A (KLA) also exhibits anti-inflammatory effect via elevated expression of HO-1 by inducing Keap1 autophagic degradation and thus facilitating Nrf2 nuclear translocation (Zhou et al., 2018)

Glutathione is also a crucial part of the livers detoxification process

Wang Q, Ge X, Tian X, Zhang Y, Zhang P