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In vitro studies have demonstrated that NRTIs also have the potential to incorporate into nuclear and mitochondrial DNA and inhibit host DNA polymerases and induce DNA damage 174,175,176,177

No wonder its @chinitaprincess favorite

Lang, J

10.1289/ehp.119-a259a 201 StrombergI.BjorklundH.DahlD.JonssonG.SundstromE.OlsonL

In a system already running low on dopaminergic tone from GLP-1 protocols, this stabilization may anchor the system further in a suppressed state rather than correcting it