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Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases

SP and HK-1 generated from macrophages, bronchial cells and mast cells cause degranulation of human mast cells via MRGPRX2, Mas-related G protein-coupled receptor-X2, which is upregulated in the lung mast cells and serum of asthmatic patients [122]

Conclusions Based on their remarkable antioxidant properties, both ALA and its reduced form DHLA are considered universal antioxidants as they act both in the membrane and in the aqueous phases

Minimize side effects by staying hydrated and resting adequately

Considering that current anti-inflammatory therapy (steroids and immunosuppressant drugs) remains unsatisfactory due to substantial side effects and uncontrolled relapses (349), understand the interaction between gut microbiota and IEB, particularly at the early subclinical phase of inflammatory disease, could be used to identify novel therapeutic approaches in chronic intestinal inflammation

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