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Interestingly, the selective deletion of SLC25A37 in hepatocytes has no phenotype under normal conditions, but it can cause protoporphyria and hepatotoxicity in delta aminolevulinic acid (a precursor of porphyrin biosynthesis)-fed animals (Troadec et al., 2011)

Metabolic diseases and bone health Emerging evidence suggests that SQOR is not confined to its traditional detoxification role, but is also deeply involved in skeletal metabolism and bone pathology

However, both can cause water retention, carpal tunnel symptoms, and effects on glucose metabolism at higher doses

On day 48, after induction of chronic ethanol intake, animals were deprived of ethanol for 14 days and thereafter allowed reaccess to ethanol solutions (10% and 20%) and water, for 2 days

Archiva Zootechnica (2010) 13(2):36

This enrichment was initiated by setting up a sulfate-reducing microbial culture in a 500 mL glass bottle sealed with a butyl rubber stopper (Step A, Fig