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Accumulating evidence has demonstrated that UA exerts potent antitumor effects by significantly inhibiting cellular proliferation, suppressing migratory capacity, and reducing clonogenic potential in SW620 cells

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This shift is underscored by recent findings that highlight the central role of context-dependent efficacy, whereby baseline nutrient status, genetic variability, and comorbid metabolic profiles critically determine clinical outcomes (Table 1

As a consequence of these dependencies, bacterial community composition is also influenced massively by different algal species 21