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Symptoms include pain, burning, tingling, numbness, weakness, or a change in sensation to light touch, pain, or temperature, or the sense of body position

Furthermore, some medicines and medical treatments (such as chemotherapy) can cause oxidative stress to rise

The current understanding of redox signaling and the intricate interplay between the various pathways involved in protection against oxidative and nitrosative stress is not complete

Instead, PerR-containing organisms often control redoxin synthesis using separate transcription factors that seem to be activated specifically by disulfide stress

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