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It is contraindicated for use in neonates and premature infants due to the risk of serious adverse reactions, including gasping syndrome

Expression of CD38 in myeloma bone niche: a rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation

You've introduced a variablethe potential for contamination with every single use

Therefore, it may contain less vitamin B12-producing bacteria to begin with

Older adults and people with compromised immune systems may need two shots because they don't mount as strong of an immune response

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