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Anticalin Technology developed by Pieris Pharmaceuticals that modifies lipocalins, which are natural extracellular proteins that bind to and transport a variety of ligands, to make therapeutics that target a specific molecule

Benzothiazole moiety was Page 68 and 69: MEDI 111 Synthesis, photophysical a Page 70 and 71: CYP450 enzymes are also involved in Page 72 and 73: Amir Nasrolahi Shirazi, ashirazi@ma Page 74 and 75: pathways and profiles and introduce Page 76 and 77: M

Six patients suffered from thalassemia major (TM), four from sickle cell disease (SCD) and two of them from severe congenital neutropenia (SCN)

GSH is synthesized in a two-step reaction catalyzed by -glutamylcysteine synthetase and GSS in the -glutamyl cycle, which includes an additional four enzymes (Figure 1)