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In some embodiments, the linking group includes a PEG moiety

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The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity

It inhibits zinc absorption by tightly binding zinc in the gut and preventing absorption into the intestine

On the surface, it seems like a minor chemical substitution

The classic KD: Fat accounts for 7075% of total calories, protein accounts for 2025%, carbohydrates account for about 5%