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Generally, it happens in middle to late adulthood and is more common in women than in men

Pharmacological preconditioning offers one of the most efficient therapeutic alternatives, preparing tissues for potential ischemic events

Dextran-conjugated triptolide and triptolide nano-MOFs enhance TNF- levels, promoting an immune response that ultimately inhibits tumor progression in pancreatic cancer with KRAS mutation, while also reducing toxicity compared to free triptolide [976, 977]