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In particular, L-carnitine reduces the expression of glial fibrillary acidic protein, inducible nitric oxide synthase, ubiquitin and caspase 3 typical markers of cell stress

Using inmmunofluorescence, we found an increased expression of SAA1, SAA2 and SOX9 in hepatocytes, an overexpression of TREM2 and MMP19 in macrophages and an overexpression of ACKR1 and PLVAP in endothelial cells in the liver biopsies of patients with AH as compared to controls

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Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure

The nutrient solution was renewed weekly, and the pH was adjusted to pH 5.5 [24]