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10 Proof-of-concept treatments were validated in Pfa1 cells, which were knocked out of endogenous GPX4 and transfected to overexpress murine mScarlet-tagged GPX4 WT (red) or GPX4 R152H (blue)

doi: 10.1038/s41467-024-45107-3 310 StussmanBCalcoBNoratoGGavinAChigurupatiSNathAet al

Nature 496 , 504507

From the four characteristic peaks obtained by fitting the spectra of Ag 3d after the addition of 0.03 mg/mL GSH in Figure 3D, it can be seen that the characteristic peaks at the binding energies of 366.58, 368.07, 372.54, and 373.86 eV are from Ag 2 S, AgO, Ag 3d, and Ag 3d3, respectively

MJo, J.O., et al., Thymosin 4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1-dependent manner