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This sharing is for informational purposes, you should definitely consult your doctor for diagnosis and treatment

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Additionally, SNRIs such as duloxetine exert their analgesic effect by enhancing serotonin (5-HT) and norepinephrine (NE)-mediated descending inhibitory systems in the spinal cord (Obata, 2017)

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based on the assessment of consumption of ASBs or tabletop sweetener packets containing aspartame only) and additionally subject to recall bias, which is inherent in the design of retrospective casecontrol studies

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