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Although we cannot extrapolate directly to the human brain, nor can we, at his point determine the exact effects of ADT, it supports the supposition that ADT would strongly influence and diminish neural activity and processing in the brain and can lead to impaired cognitive ability, which should not be ignored in the quality-of-life measurements of patients undergoing ADT for PCa therapy

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Bridging mechanistic discoveries with patient-centered outcomes through precision phenotyping, integrative therapies, and innovative trial design may ultimately establish metabolic modulation as a cornerstone in HF management

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[] Accumulating evidence has shown that OS, which is considered one of the predisposing factors of PCOS, plays an essential role in insulin resistance, various metabolic diseases, and chronic inflammation