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J Am Nutr Assoc

Analysis of senescent cells damaged in the upper dermis revealed the presence of p38 MAPK, highlighting the significance of senescence in the continual pigmentation seen in melasma

Free Radic Biol Med 34:145169 Imai H, Hirao F, Sakamoto T, Sekine K, Mizukura Y, Saito M, Kitamoto T, Hayasaka M, Hanaoka K, Nakagawa Y (2003) Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene