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doi: 10.1371/JOURNAL.PGEN.1002552 190 BergholdtRBrorssonCPallejaABerchtoldLAFlyelTBang-BerthelsenCHet al

Preclinical and some clinical evidence suggest that readers should consider any benefits as tentative and anticipate results to vary in practice

Thus, the absence of metastasis in the triple therapy group may be partially due to the loss of cancer cells (secondary to the cytotoxic effect of gemcitabine) and the decreased stemness of the surviving cells due to HGF/c-MET inhibition