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This includes recognising signs of a flare-up and facilitating appropriate referral to primary or secondary care services for review

Standard maintenance dosing is 350 to 1000 mcg per day

Experts suggest that not only are more people taking supplements, but theyre also taking more of them, with ingredient combinations and higher doses leading to liver injury in some individuals

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Gastrointestinal effects are the most frequently reported side effects and include: Nausea (1224% of patients): Often most pronounced during treatment initiation and dose escalation, typically improving over time Diarrhea (1323% of patients): May be transient or persistent, requiring dietary modifications Vomiting (611% of patients): Can lead to dehydration if severe or prolonged Constipation (617% of patients): May require increased fiber intake and hydration Abdominal pain or discomfort (610% of patients): Usually mild to moderate in severity Decreased appetite : Therapeutic effect but may be excessive in some individuals These gastrointestinal symptoms generally diminish over several weeks as the body adjusts to the medication

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