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Data analysis Raw files were searched through Proteome Discoverer v.2.3 (Thermo Scientific) and spectra were queried against the human proteome (database downloaded from uniprot.org on 02/12/2019, containing 73662 sequences) using Sequest HT with a 1 % false discovery rate (FDR) applied

In the context of transcriptomic analyses, it is generally observed that GST expression is downregulated in susceptible interactions ( A

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[8] Niacinamide Dietary requirements for niacin can be met by the ingestion of either nicotinic acid or nicotinamide

However, under pathological conditions, activated MMPs are associated with increased degradation of ECM components and are involved in ECM re-modeling (Dollery et al., 40 oligomers can increase MMP-2 activity in stimulated astrocytes and correlated with increased oxidative stress, inflammation and reduced cell viability

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