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10.3390/microorganisms8050784 [DOI] [PMC free article] [PubMed] [Google Scholar] Ochoa-Repraz J., Mielcarz D

Subsequent inhibition of WEE1 G2 checkpoint kinase (WEE1) kinase results in synthetic lethality, highlighting how manipulating upstream or downstream pathways of CYP51A1 may promote selective cancer cell death [102]

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Sieglinde Klaus References Pickart L., Margolina A

Key considerations often include: Individual biological context, such as sleep patterns and circadian stability Overall stress exposure and recovery capacity General metabolic and inflammatory status The intended purpose of use within a broader longevity strategy For this reason, Epitalon is commonly applied in defined cycles with clear boundaries, rather than as a long-term or indefinite therapy