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Zhang, [email protected] This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This phenomenon is known as oncogene addiction and applies to all settings where cancer cells appear to be dependent on a single overactive oncogene for their proliferation and survival [Sharma et al