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Simvastatin and the Rho-Kinase Inhibitor Y-27632 Prevent Myofibroblast Transformation in Peyronie;s Disease-Derived Fibroblasts via Inhibition of YAP/TAZ Nuclear Translocation

However, given the observational designs, small sample sizes, and lack of control for natural history of placebo effects, these findings require replication in randomized adequately-powered designs