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CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

On the other hand, activation of the SNS in turn activates peripheral leukocytes to promote expression of NF-B-mediated pro-inflammatory immune response genes such as IL-1, IL-6, and TNF- via adrenaline and noradrenaline, which may generate an inflammatory environment in the periphery (Amit et al., 2009

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The fact that cysteine S -conjugate -lyase activity is widespread in enteric bacteria and that a major portion of cysteine S -conjugates are excreted into the bile suggests that the gut flora may be important for the incorporation of sulfur into some xenobiotics (Larsen and Stevens, 1986)