glutathione and lupus together Autoimmune Disease Overview of Oxidative Stress in

Expert Rev Clin Immunol 7(3):287294

Under oxidative stress and induced by excessive ROS generation, Nrf2 is released from its inhibitor Keap1, allowing its translocation into the nucleus (Kasprzak et al., 2020), where it binds to the antioxidant response element (ARE) present in the DNA sequence of numerous antioxidant enzymes like glutathione-S-transferase, -glutamyl cysteine synthetase (glutamate cysteine ligase), heme oxygenase 1, and paraoxonase-1 inducing their transcription, managing the phase II response to oxidative stress (Kasprzak et al., 2020)

doi:10.1023/A:1023768811842

Alkhuder K, Meibom KL, Dubail I, Dupuis M, Charbit A

If you have any questions about risks and side effects, please read the patient information leaflet and ask your doctor or pharmacist

In summary, we advocate the healthy modulation of oxidative stress in older CAP patients to achieve the desired therapeutic assistance rather than simply inhibiting and scavenging free radicals