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Clinical analysis of compound glycyrrhizin in the treatment of anti-tuberculosis drug-induced hepatitis

however, phytochemicals can disrupt the Nrf-2Keap1 interaction, allowing Nrf-2 to translocate into the nucleus

The principal conformational changes are the ~54 outward splaying of TM1a and further unwinding of the intracellular side of TM5 in the inward-open conformation (Fig