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Description

Acuna-Castroviejo, D

Liproxstain-1 (Lip-1), a spiroquinoxalinamine derivative, was identified as a special ferroptostic inhibitor by high-throughput screening

doi: 10.1016/j.bbrc.2013.04.047 44 PearceELPearceEJ

This strategy may be useful to enhance pharmacokinetic properties (ADME), as well as poor aqueous solubility, which clears a critical step in pre-clinical phase drug development