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It has been demonstrated that, together with the regulation of CPT1 by malonyl-CoA, acetylation of CACT plays a crucial role in the control of the influx of fatty acyl units into mitochondria 57

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People who are pregnant or breastfeeding, those with kidney disease, seizure disorders, or thyroid conditions, and anyone on medications that could interact should avoid it unless a physician specifically approves it

Cavallini G, et al

The role of haptoglobin polymorphism in cardiovascular disease in the setting of diabetes