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Extracellular vesicles from individuals with endometriosis-associated infertility significantly inhibited the total motility, progressive motility, linear velocity, and the acrosome reaction rate of human sperm by inducing the production of inflammatory cytokines leading to a Th17/regulatory T cell (Treg) imbalance (83)

Vitamin B12 injections may offer a safer alternative for patients concerned about side effects

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This overlap opens the discussion about the possibility of common pathogenic pathway.[2] References: 1

As a side note, AUC is the best way to measure bioavailability because it takes into account the entire response over time, whereas Cmax, which is used by some researchers, measures only one point in time and is, therefore, less reliable