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2021 NEJM) and 20.9% in SURMOUNT-1 (Jastreboff et al

On the other hand, AGEs bind to the RAGE on the RPE cell membrane, disrupting iron metabolic homeostasis and accelerating the ferroptosis process in RPE cells (183185)

Includes: Vitamin B complex, Vitamin C, Magnesium, Zinc, and fluids

10.1093/nar/gkab1224 43 FedoreyevaL

H., Macintyre, G., Wedge, D

Peer review Peer review information Nature Immunology thanks Jatin Vyas, Borko Amulic, Gordon Brown, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work