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Extracellular cysteine can also directly be taken up by cultured astrocytes and used for GSH synthesis, but its disulfide cystine, that is transported into rat astrocytes mainly by the cystineglutamate antiporter X C , serves as the preferred extracellular substrate for the cytosolic cysteine needed for astrocytic GSH synthesis (Kranich et al

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10.1016/j.tox.2016.08.016 118 Pogrmic-MajkicK.SamardzijaD.Stojkov-MimicN.VukosavljevicJ.Trninic-PjevicA.KopitovicV.et al (2018)