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Strengths of this T1D trial were the recruitment of young patients within 5 weeks of diagnosis and the inclusion of a combination antigen (GAD-alum) plus GABA study group (151), in combination with non-ideal study drug adherence, it is possible that islet GABA exposure was insufficient to achieve an anti-diabetic effect

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Notably, in animals primed with L-dopa + BZ, MPE alone mitigated DID severity

To ensure public safety, the FDA has defined Good Manufacturing Practices (GMPs) that it enforces through inspections, and has the authority to prosecute, seize and remove dangerous products from the marketplace

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