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We need quantitative links between local LIP, PUFA-PL composition (ACSL4/LPCAT3) and anti-ferroptotic circuits (GPX4, FSP1/DHODH), to predict where/when H 2 O 2 becomes Fenton-competent and when ferroptosis ignites

PubMed Safer, D., Elzinga, M., Nachmias, V.T

J Biol Chem 271:1677316783 Ohshima K, Montermini L, Wells RD, Pandolfo M (1998) Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo

Alternatively, it is also possible that altered redox regulation might be present only in distinct subgroups of autistic individuals

And avoid slathering a thick layer of lotion or balm on the tattoo