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Previously, they had demonstrated the effectiveness of another PDE4i, CC-3052, in combination with isoniazid for the treatment of rabbit tuberculosis (101, 102)

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A two-arm pragmatic RCT with 233 IBS patients who were an average duration of 13 years found that compared with usual care, acupuncture treatment significantly reduced the IBS Symptom Severity Score (IBS-SSS) at 3 months [124]

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If you work in a high-stress or emotionally difficult job (for example, paramedics, firefighters, social workers, etc.), it may also be helpful to talk about a return to work with your pain psychologist