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The most popular therapeutic use of CAP in clinical application is pain relief

Although the degree of inflammation in OA is generally lower than in rheumatoid arthritis, synovial tissue can still exhibit marked hyperplasia and inflammatory cell infiltration ( Accompanying inflammation and mechanical damage, oxidative stress and multiple forms of cell death are deeply involved in the molecular mechanisms driving OA progression ( Figure 1 )

Urinary excretion is the primary route of elimination of 5-azacitidine and its metabolites