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Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients

With increased FKBP51expression, as in stressful situations and in MDD itself, the GR responds less efficiently, and negative feedback on the HPA axis is impaired, thereby maintaining the system in prolonged activation

The indispensable role of the C terminal domain in preventing fibrillation has been demonstrated by an engineered -synuclein with truncated C terminus which not only displayed accelerated fibrillation kinetics but also promoted the phase separation of WT -synuclein (Huang et al., 2022)

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elegans , whereas the AsCSR-1 pathways appear to function similarly as in C

Evidence That Hydrogen Sulphide can Modulate Hypothalamo-Pituitary-Adrenal Axis Function: In Vitro and In Vivo Studies in the Rat