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Continuation of semaglutide resulted in a further 7.9% reduction in body weight from their week 20 weight, whereas the placebo group regained 6.9% [92]

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Its most-studied use is in combination: co-administered with semaglutide (CagriSema), weight loss reached 15.6% at 32 weeks far beyond semaglutide alone (5.1%)[2]

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Intra-AP treatment with the amylin antagonist AC 187 inhibits the anorectic actions of peripherally administered amylin