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Tirzepatide is the first combination of entero-pancreatic hormones [dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) RA] that has been approved for T2D management based on the findings from the phase 3 SURPASS programme

Adults in the combination cagrilintide and semaglutide group had reductions in total cholesterol, triglycerides, LDL cholesterol, VLDL cholesterol and high-sensitivity C-reactive protein, and an increase in HDL cholesterol

The peptide has been investigated for its involvement in signal transduction processes, peptide-receptor interactions, and molecular regulatory systems associated with neuropeptide biology

10.1080/09595230801919494 59 LeongH

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