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Treatment of zebrafish embryos with copper nanoparticles and copper sulfate results in the reduced inner mitochondrial membrane and increased vesicle formation, disordered endoplasmic reticulum structure, increased reactive oxygen species, elevated levels of active caspase-3, and decreased levels of Bcl2, leading to cell apoptosis and retinal developmental defects

Treatment with pembrolizumab in programmed death ligand 1positive recurrent glioblastoma: Results from the multicohort phase 1 KEYNOTE-028 trial