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While well controlled studies are not yet available, the use of xylazine as a street drug has been associated with the development of severe wounds that erupt with a scaly dead tissue called eschar , which if left untreated can result in the need for amputation

However, it is only recently that the mechanisms responsible for this metabolic reprogramming have been elucidated in more detail

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Results can vary based on individual skin types and the severity of scars

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