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The histology of lumbar intervertebral disc herniation

Mitochondrial and metabolic dysfunction of peripheral immune cells in multiple sclerosis

Without enough reduced glutathione to neutralize these byproducts, the immune cells can become sluggish

Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79

However, a significant number of variants detected in patients with cholestatic liver disease fall into the VUS category, where it remains unclear whether the variant contributes to the patients phenotype [68]