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Considering the importance of -crystallin (formed by two subunits, A and B) for maintaining the structural organization of the lens, synthetic peptides derived from this protein (mini-A and mini-B) have been generated, proving to be equally effective in preventing protein aggregation and precipitation [129] (Table 1)

Smith found Pissenem on the roof of the [UNVRS] construction site holding a drone controller

Journal of Toxicology , 2012

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During a clinical study on patients with Gauchers disease (GD), a rare lysosomal storage disorder, this risk factor was identified

Practical readouts to separate signalling from damage Practical readouts to separate signalling from damage combine signalling proxiessuch as reversible cysteine oxidation mapped by redox proteomics, the redox state of peroxiredoxins as fast cycling sentinels, compartment-targeted H 2 O 2 reporters that resolve matrix/ER/PM microdomains and phospho-signatures downstream of redox-sensitive kinaseswith damage proxies including lipid-peroxidation adducts, protein carbonyls or nitrotyrosine, DNA oxidation and strand breaks and indices of bioenergetic failure (Garrido Ruiz et al