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Similar content being viewed by others Introduction Dementia has emerged as a global health challenge

Barrier dysfunction increases epithelial permeability, enabling inflammatory cytokines to penetrate deeper tissues and exacerbate intraepithelial damage

qtot 0.09 49 HGA2 1 ful H49 49 0.09 1.008

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Sleeping well, exercising regularly and only drinking alcohol in moderation (the liver uses glutathione as a detoxifier) are also important

The role of EGFR in suppressing oxidative stress markers in an animal model of Parkinsons disease has also been clarified by a recent study, using Lapatinib (LAP), an anti-cancer drug that acts by mediating oxidative stress, with proven neuroprotective effects in case of epilepsy 37 .They observed that LAP restored glutathione/glutathione peroxidase (GSH/GPx) through the suppression of p-EGFR/c-SRC/PKCII/PLC-/ACSL-4 and PTGS2 38