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Vegans and Vegetarians: Since B12 is almost exclusively in animal products, those on plant-based diets are at high risk

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CDC summarizes USP guidance: date an opened multi-dose vial at first puncture and discard it within 28 days unless the manufacturer states another opened-vial date. The dose count and 28-day window together require three vials for the 12-week protocol

- polyneuropathy of various origins - neuritis and neuralgia - radiculoneuritis due to degenerative diseases of the spine (cervical syndrome, hand and forearm cider, lumbar syndrome) - sciatica - trigeminal neuralgia, intercostal neuralgia The drug is injected only intramuscularly (in the upper outer quadrant of the gluteus maximus muscle)