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Guidelines for various treatments for different groups of patients with relapsed or refractory MM and drug-resistant MM, including single-agent and combined therapies, are needed to set clinical standards and reduce the economic burden on patients

[DOI] [PubMed] [Google Scholar] 71.Tonnesen HH, and Karlsen J

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Mechanistically, AUR disrupts redox-homeostasis by irreversibly binding to the selenocysteine active site of intracellular TrxR, thereby inhibiting Trx reduction and impairing ROS detoxification [38]

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The country has failed to build an inclusive society due to successive governments (and their voters) insistence on Sinhala-Buddhist supremacy, and the resultant ethnocratic nature of the state and its institutions as protectors of the Sinhalese community, at the expense of Tamils and Muslims