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In this context, CD45 phosphatase dephosphorylates and inactivates STAT3, thereby attenuating the expansion and suppressive function of MDSCs

Drexler HG, Matsuo Y

Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death

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Compelling evidence has shown that oncogene-induced replication stress and dNTP exhaustion 30,31