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Poznyak AV, Nikiforov NG, Markin AM, Kashirskikh DA, Myasoedova VA, Gerasimova EV, et al

Statins inhibit HMG-CoA reductase, decreasing ergosterol synthesis and impairing biofilms in Candida , Aspergillus , and zygomycetes, often synergizing with fluconazole (Macreadie et al., 2006

Increased Intestinal Permeability and Immune Activation COVID-19 damages intestinal barrier integrity, leading to increased permeability or leaky gut. Studies reveal elevated levels of several permeability markers, including fatty acid-binding protein 2 and lipopolysaccharide-binding protein in COVID-19 patients

Biochemical and structural studies demonstrated that this Arg residue is essential for the Fe/S domain

The downregulation of antioxidant pathways has also been associated with acute exacerbations of COPD 49

doi: 10.1038/s41421-021-00258-1 177 MagnaniH