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Kaunitz Current Opinion in Gastroenterology.2016

Therefore, in the present study, we demonstrated that serum GPX-3 concentration at diagnosis has the potential to be a novel biomarker that can assess and estimate activity and damage caused by AAV, although it is confined to the time of diagnosis

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doi: 10.1038/s41579-023-00904-3 51

The first step is the unusual coupling of the gamma-carboxylic acid of glutamic acid to cysteine by the enzyme gamma-glutamylcysteine synthase to form gamma-glutamylcysteine