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Description

Dysfunctional mitochondria generate excessive ROS, mtDNA instability, and oncogenic signaling

LPS-induced IL-10 production in whole blood cultures from chronic fatigue syndrome patients is increased but supersensitive to inhibition by dexamethasone

Science 350 , 203207 (2015)

The 93% amino acid identity between human and rat orthologs suggested that CYP51A1 functions as a highly conserved housekeeping enzyme essential for survival [13, 14]