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These peripheral and central deficits can include severe gastrointestinal lesions, intracranial (superior sagittal sinus) hypertension, brain swelling and lesions, portal and caval hypertension, aortic hypotension, peripheral and central thrombosis, inferior caval vein and superior mesenteric vein congestion, azygos vein failure, electrocardiogram (ECG) disturbances, and heart, lung, liver, and kidney lesions (Vukojevic et al., 2018

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doi: 10.3389/fnut.2024.1493593 Received 09 September 2024 Accepted 18 October 2024 Published 08 November 2024 Volume 11 - 2024 Edited by Syeda Mahvish Zahra, Allama Iqbal Open University, Pakistan Reviewed by Farzana Saleh, Bangladesh University of Health Sciences, Bangladesh Nilfer zkan, Ordu University, Trkiye Updates Copyright 2024 Memon, Conti, Brilli, Tarantino, Chaudhry, Baloch, Shafiq, Mumtaz, Qaisar, Iqtadar, Abrar, Kanwal, Akhtar, Latif, Rabbani, Ujjan, Turroni and Khan

Once reconstituted, the peptide should not be frozen