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Chronic intestinal inflammation in AS often occurs without overt gastrointestinal symptoms, yet is associated with worse spinal inflammation and can even drive progression from early axial spondyloarthritis to established AS[13]

Vitamin E alleviated adverse effects of immobilization stress in an animal model (Asir 2022) Licorice root 500 mg two to three times daily (Stengler 2016) May increase cortisol levels by inhibiting an enzyme that converts cortisol into cortisone effects (Omar 2012)